A dual functional probe for assessing human CYP450 3A5 and 3A enzymes bioactivities.

导出 LinkOut

翻译打印收藏纠错

作者： Fei,Yan ^[1] ; Yonglei,Cui ^[1] ; Yue,An ^[2] ; Jing,Ning ^[3] ; Xinyu,Zhao ^[1] ; Lei,Feng ^[1] ; Xiaokui,Huo ^[1] ; Chao,Wang ^[1] ; Chuanzhu,Lv ^[1] ; Xiaochi,Ma ^[4] ; Xiangge,Tian ^[1]

作者单位： Academy of Integrative Medicine, College of Pharmacy, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, PR China. ^[1] Preparation Department, Ningxia Hui Autonomous Region Hospital of Traditional Chinese Medicine, Yinchuan 750021, PR China. ^[2] Clinical Laboratory, The Second Affiliated Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian City, Liaoning Provinc, PR China. ^[3] Institute of Functional Materials & Molecular Imaging, College of Emergency & Trauma, Hainan Medical University, No. 3 Xueyuan Road, Longhua District, Haikou, Hainan, PR China. ^[4]

关键词 3-isobutyryl-11-keto-β-boswellic acid CYP3A5 dual functional probe high selectivity

主题词色谱法, 液相(Chromatography, Liquid);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);人类(Humans);动力学(Kinetics);分子探针(Molecular Probes);串联质谱法(Tandem Mass Spectrometry)

DOI 10.4155/fmc-2019-0173

PMID 31702381

发布时间 2020-08-06

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交