换一批
换一批Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ.
第一作者：
Zhi-Hao,Zhang
第一单位：
State Key Laboratory of Natural Medicines, Department of TCMs Pharmaceuticals, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China. zzh-198518@163.com.
作者：
主题词
投药, 口服(Administration, Oral);酰苯胺类(Anilides);动物(Animals);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);纤维化(Fibrosis);肾疾病(Kidney Diseases);配体(Ligands);男(雄)性(Male);小鼠(Mice);小鼠, 近交ICR(Mice, Inbred ICR);分子结构(Molecular Structure);PPARγ(PPAR gamma);五环三萜类(Pentacyclic Triterpenes);前列腺素D2(Prostaglandin D2);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);构效关系(Structure-Activity Relationship);输尿管梗阻(Ureteral Obstruction)
DOI
10.1038/s41401-019-0319-4
PMID
31705123
发布时间
2021-01-10
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Acta pharmacologica Sinica
373-382页
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