A novel isothiocyanate derivative inhibits HIV-1 gene expression and replication by modulating the nuclear matrix associated protein SMAR1.-论文-万方医学网

作者： Jay,Trivedi ^[1] ; Aftab,Alam ^[2] ; Shruti,Joshi ^[3] ; Togapur Pavan,Kumar ^[4] ; Venkatraju,Chippala ^[5] ; Prathama S,Mainkar ^[6] ; Srivari,Chandrasekhar ^[7] ; Samit,Chattopadhyay ^[8] ; Debashis,Mitra ^[9]

作者单位： National Centre for Cell Science, Pune University Campus, Pune, India. Electronic address: jay.nccs@yahoo.com. ^[1] National Centre for Cell Science, Pune University Campus, Pune, India. Electronic address: affy1grd@gmail.com. ^[2] National Centre for Cell Science, Pune University Campus, Pune, India. Electronic address: shruti86joshi@gmail.com. ^[3] CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India. Electronic address: pavantogapur@gmail.com. ^[4] CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India. Electronic address: ch.vraju1@gmail.com. ^[5] CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India. Electronic address: prathama@iict.res.in. ^[6] CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India. Electronic address: srivaric@iict.res.in. ^[7] National Centre for Cell Science, Pune University Campus, Pune, India; CSIR-Indian Institute of Chemical Biology, Jadavpur, Kolkata, India. Electronic address: samit@iicb.res.in. ^[8] National Centre for Cell Science, Pune University Campus, Pune, India; Centre for DNA Fingerprinting and Diagnostics, Uppal, Hyderabad, India. Electronic address: dmitra@nccs.res.in. ^[9]

主题词抗HIV药(Anti-HIV Agents);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);DNA结合蛋白质类(DNA-Binding Proteins);剂量效应关系, 药物(Dose-Response Relationship, Drug);基因表达调控, 病毒(Gene Expression Regulation, Viral);HIV感染(HIV Infections);HIV长末端重复序列(HIV Long Terminal Repeat);HIV-1(HIV-1);宿主与病原体相互作用(Host-Pathogen Interactions);人类(Humans);异硫氰酸盐类(Isothiocyanates);分子结构(Molecular Structure);核蛋白质类(Nuclear Proteins);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);转录, 遗传(Transcription, Genetic);病毒载量(Viral Load);病毒复制(Virus Replication)

DOI 10.1016/j.antiviral.2019.104648

PMID 31706900

发布时间 2020-09-28

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A novel isothiocyanate derivative inhibits HIV-1 gene expression and replication by modulating the nuclear matrix associated protein SMAR1.

Antiviral research

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Antiviral research

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A novel isothiocyanate derivative inhibits HIV-1 gene expression and replication by modulating the nuclear matrix associated protein SMAR1.

Antiviral research

相似文献

Antiviral research

相关期刊

检索历史清除