Design, synthesis and characterization of a PEGylated stanozolol for potential therapeutic applications.

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作者： Cristian,Vergallo ^[1] ; Giulia,Torrieri ^[2] ; Riccardo,Provenzani ^[2] ; Sini,Miettinen ^[3] ; Karina,Moslova ^[4] ; Markku,Varjosalo ^[3] ; Maria Chiara,Cristiano ^[5] ; Massimo,Fresta ^[6] ; Christian,Celia ^[7] ; Hélder A,Santos ^[8] ; Felisa,Cilurzo ^[9] ; Luisa,Di Marzio ^[1]

作者单位： Department of Pharmacy, University of Chieti - Pescara "G. d'Annunzio", Via dei Vestini 31, I-66100 Chieti, Italy. ^[1] Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, FI-00014 Helsinki, Finland. ^[2] Institute of Biotechnology, University of Helsinki, FI-00014 Helsinki, Finland. ^[3] Department of Chemistry, University of Helsinki, FI-00014 Helsinki, Finland. ^[4] Department of Experimental and Clinical Medicine, University of Catanzaro "Magna Graecia", Viale Europa, Via "S. Venuta" s.n.c., I-88100 Catanzaro, Italy. ^[5] Department of Health Sciences, University of Catanzaro "Magna Graecia", Via "S. Venuta" s.n.c., I-88100 Catanzaro, Italy. ^[6] Department of Pharmacy, University of Chieti - Pescara "G. d'Annunzio", Via dei Vestini 31, I-66100 Chieti, Italy. Electronic address: c.celia@unich.it. ^[7] Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, FI-00014 Helsinki, Finland; Helsinki Institute of Life Science (HiLIFE), University of Helsinki, FI-00014 Helsinki, Finland(g). Electronic address: helder.santos@helsinki.fi. ^[8] Department of Pharmacy, University of Chieti - Pescara "G. d'Annunzio", Via dei Vestini 31, I-66100 Chieti, Italy. Electronic address: felisa.cilurzo@unich.it. ^[9]

关键词 Biopolymers Conjugated drug delivery systems PEGylation Polyethylene glycol (PEG) derivatives Stanozolol