Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer's disease.

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作者： Dong Kyu,Kim ^[1] ; Dohyun,Han ^[2] ; Joonho,Park ^[3] ; Hyunjung,Choi ^[4] ; Jong-Chan,Park ^[1] ; Moon-Yong,Cha ^[5] ; Jongmin,Woo ^[1] ; Min Soo,Byun ^[6] ; Dong Young,Lee ^[7] ; Youngsoo,Kim ^[8] ; Inhee,Mook-Jung ^[9]

作者单位： Department of Biomedical Sciences, Seoul National University, College of Medicine, Seoul, Korea. ^[1] Proteomics Core Facility, Transdisciplinary Research and Collaboration, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea. ^[2] Interdisciplinary Program for Bioengineering, Seoul National University, College of Engineering, Seoul, Korea. ^[3] Interdisciplinary Graduate Program in Genetic Engineering, Seoul National University, Seoul, Korea. ^[4] LG Chem Life Science R&D Campus, Drug Discovery Center, Seoul, Korea. ^[5] Institute of Human Behavioral Medicine, Medical Research Center, Seoul National University, Seoul, Korea. ^[6] Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea. ^[7] Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea. ^[8] Department of Biomedical Sciences, Seoul National University, College of Medicine, Seoul, Korea. biolab@snu.ac.kr. ^[9] Interdisciplinary Program for Bioengineering, Seoul National University, College of Engineering, Seoul, Korea. biolab@snu.ac.kr. ^[10] Department of Biomedical Sciences, Seoul National University, College of Medicine, Seoul, Korea. inhee@snu.ac.kr. ^[11]