Bayesian shrinkage estimation of high dimensional causal mediation effects in omics studies.

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作者： Yanyi,Song ^[1] ; Xiang,Zhou ^[1] ; Min,Zhang ^[1] ; Wei,Zhao ^[2] ; Yongmei,Liu ^[3] ; Sharon L R,Kardia ^[2] ; Ana V Diez,Roux ^[4] ; Belinda L,Needham ^[2] ; Jennifer A,Smith ^[2] ; Bhramar,Mukherjee ^[1]

作者单位： Department of Biostatistics, University of Michigan, Ann Arbor, Michigan. ^[1] Department of Epidemiology, University of Michigan, Ann Arbor, Michigan. ^[2] Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina. ^[3] Department of Epidemiology and Biostatistics, Drexel University, Philadelphia, Pennsylvania. ^[4]

关键词 Bayesian sparse models continuous shrinkage epigenetics high-dimensional mediators

主题词贝叶斯定理(Bayes Theorem);因果律(Causality);DNA甲基化(DNA Methylation);模型, 统计学(Models, Statistical)

DOI 10.1111/biom.13189

PMID 31733066

发布时间 2024-09-22

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