What Do Neighbors Tell About You: The Local Context of Cis-Regulatory Modules Complicates Prediction of Regulatory Variants.

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第一作者： Dmitry D,Penzar

第一单位： Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.

作者： Dmitry D,Penzar ^[1] ; Arsenii O,Zinkevich ^[2] ; Ilya E,Vorontsov ^[3] ; Vasily V,Sitnik ^[1] ; Alexander V,Favorov ^[2] ; Vsevolod J,Makeev ^[1] ; Ivan V,Kulakovskiy ^[1]

作者单位： Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia. ^[1] Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia. ^[2] Department of Medical and Biological Physics, Moscow Institute of Physics and Technology (State University), Dolgoprudny, Russia. ^[3] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, United States. ^[4] Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. ^[5] Institute of Mathematical Problems of Biology RAS - the Branch of Keldysh Institute of Applied Mathematics of Russian Academy of Sciences, Pushchino, Russia. ^[6]

关键词 enhancers machine learning promoters rSNP regulatory variants saturation mutagenesis massively parallel reporter assay

DOI 10.3389/fgene.2019.01078

PMID 31737053

发布时间 2023-10-19

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Frontiers in genetics

2019年10卷

1078页

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What Do Neighbors Tell About You: The Local Context of Cis-Regulatory Modules Complicates Prediction of Regulatory Variants.

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What Do Neighbors Tell About You: The Local Context of Cis-Regulatory Modules Complicates Prediction of Regulatory Variants.

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