Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts.

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作者： Angelica,Avagliano ^[1] ; Maria Rosaria,Ruocco ^[2] ; Rosarita,Nasso ^[2] ; Federica,Aliotta ^[3] ; Gennaro,Sanità ^[2] ; Antonino,Iaccarino ^[2] ; Claudio,Bellevicine ^[1] ; Gaetano,Calì ^[1] ; Giuseppe,Fiume ^[4] ; Stefania,Masone ^[5] ; Mariorosario,Masullo ^[6] ; Stefania,Montagnani ^[3] ; Alessandro,Arcucci ^[1]

作者单位： Department of Public Health, University of Naples Federico II, 80131 Naples, Italy. ^[1] Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy. ^[2] Department of Movement Sciences and Wellness, University of Naples 'Parthenope', 80133 Naples, Italy. ^[3] IEOS Istituto di Endocrinologia e Oncologia Sperimentale 'G. Salvatore', National Council of Research, 80131 Naples, Italy. ^[4] Department of Experimental and Clinical Medicine, University of Catanzaro 'Magna Graecia', Viale Europa, 88100 Catanzaro, Italy. ^[5] Department of Clinical Medicine and Surgery, University of Naples Federico II, 80133 Naples, Italy. ^[6]

关键词 conditioned medium melanoma proto-myofibroblasts stromal microenvironment

主题词肌动蛋白类(Actins);成年人(Adult);细胞间通讯(Cell Communication);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞存活(Cell Survival);细胞, 培养的(Cells, Cultured);培养基, 条件性(Culture Media, Conditioned);环氧化酶2(Cyclooxygenase 2);女(雌)性(Female);人类(Humans);黑色素瘤(Melanoma);中年人(Middle Aged);肌成纤维细胞(Myofibroblasts);表型(Phenotype);球形体, 细胞(Spheroids, Cellular);肿瘤微环境(Tumor Microenvironment);波形蛋白(Vimentin)

DOI 10.3390/cells8111435

PMID 31739477

发布时间 2020-07-22

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2019年8卷11期

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Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts.

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Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts.

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