Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels.

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作者： Evan P,Taddeo ^[1] ; Nour,Alsabeeh ^[1] ; Siyouneh,Baghdasarian ^[2] ; Jakob D,Wikstrom ^[1] ; Eleni,Ritou ^[3] ; Samuel,Sereda ^[1] ; Karel,Erion ^[4] ; Jin,Li ^[1] ; Linsey,Stiles ^[1] ; Muhamad,Abdulla ^[1] ; Zachary,Swanson ^[5] ; Joshua J,Wilhelm ^[5] ; Melena D,Bellin ^[5] ; Richard G,Kibbey ^[5] ; Marc,Liesa ^[6] ; Orian S,Shirihai ^[7]

作者单位： Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA. ^[1] Department of Physiology, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait. ^[2] Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, and Department of Dermato-Venereology, Karolinska University Hospital, Stockholm, Sweden. ^[3] Endocrinology, Diabetes, Nutrition and Weight Management Section, Department of Medicine, Boston University School of Medicine, Boston, MA. ^[4] Department of Surgery and Schulze Diabetes Institute, University of Minnesota School of Medicine, Minneapolis, MN. ^[5] Division of Pediatric Endocrinology, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN. ^[6] Departments of Internal Medicine (Endocrinology) and Cellular & Molecular Physiology, Yale University, New Haven, CT. ^[7] Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA mliesa@mednet.ucla.edu oshirihai@mednet.ucla.edu. ^[8] Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA. ^[9]