Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments.

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作者： Barrett D,Allen ^[1] ; Lauren A,Apodaca ^[1] ; Amber R,Syage ^[1] ; Mineh,Markarian ^[1] ; Al Anoud D,Baddour ^[1] ; Harutyun,Minasyan ^[1] ; Leila,Alikhani ^[1] ; Celine,Lu ^[1] ; Brian L,West ^[2] ; Erich,Giedzinski ^[1] ; Janet E,Baulch ^[1] ; Munjal M,Acharya ^[3]

作者单位： Department of Radiation Oncology, University of California, Medical Sciences I, Room B-149, Irvine, CA, 92697-2695, USA. ^[1] Plexxikon Inc., Berkeley, CA, USA. ^[2] Department of Radiation Oncology, University of California, Medical Sciences I, Room B-149, Irvine, CA, 92697-2695, USA. macharya@uci.edu. ^[3]

关键词 Adriamycin Chemobrain Chemotherapy Cognitive dysfunction Colony stimulating factor receptor 1 Doxorubicin Extracellular vesicles Induced pluripotent stem cells Microglia Neuroinflammation

主题词动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);多柔比星(Doxorubicin);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);炎症(Inflammation);炎症介导素类(Inflammation Mediators);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);有机化学品(Organic Chemicals);受体, 粒细胞巨噬细胞集落刺激因子(Receptors, Granulocyte-Macrophage Colony-Stimulating Factor)

DOI 10.1186/s40478-019-0838-8

PMID 31753024

发布时间 2020-09-25

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Acta neuropathologica communications

2019年7卷1期

186页

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Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments.

Acta neuropathologica communications

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Acta neuropathologica communications

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Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments.

Acta neuropathologica communications

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Acta neuropathologica communications

相关期刊

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