首页> ACS chemical neuroscience> Spatial Lipidomics Reveals Region and Long Chain Base Specific Accumulations of Monosialogangliosides in Amyloid Plaques in Familial Alzheimer's Disease Mice (5xFAD) Brain.

Spatial Lipidomics Reveals Region and Long Chain Base Specific Accumulations of Monosialogangliosides in Amyloid Plaques in Familial Alzheimer's Disease Mice (5xFAD) Brain.

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第一作者： Ibrahim,Kaya

第一单位： Department of Psychiatry and Neurochemistry , Sahlgrenska Academy at the University of Gothenburg , Mölndal 43180 , Sweden.;Department of Chemistry and Molecular Biology , University of Gothenburg , Gothenburg 405 30 , Sweden.;The Gothenburg Imaging Mass Spectrometry (Go:IMS) Platform , University of Gothenburg and Chalmers University of Technology , Gothenburg , Sweden.

作者： Ibrahim,Kaya ^[1] ; Eva,Jennische ^[2] ; Johan,Dunevall ^[3] ; Stefan,Lange ^[2] ; Andrew G,Ewing ^[4] ; Per,Malmberg ^[3] ; Ahmet Tarik,Baykal ^[5] ; John S,Fletcher ^[4]

作者单位： Department of Psychiatry and Neurochemistry , Sahlgrenska Academy at the University of Gothenburg , Mölndal 43180 , Sweden.;Department of Chemistry and Molecular Biology , University of Gothenburg , Gothenburg 405 30 , Sweden.;The Gothenburg Imaging Mass Spectrometry (Go:IMS) Platform , University of Gothenburg and Chalmers University of Technology , Gothenburg , Sweden. ^[1] Institute of Biomedicine , University of Gothenburg , Gothenburg 405 30 , Sweden. ^[2] Department of Chemistry and Chemical Engineering , Chalmers University of Technology , Gothenburg 412 96 , Sweden. ^[3] Department of Chemistry and Molecular Biology , University of Gothenburg , Gothenburg 405 30 , Sweden.;The Gothenburg Imaging Mass Spectrometry (Go:IMS) Platform , University of Gothenburg and Chalmers University of Technology , Gothenburg , Sweden. ^[4] Department of Medical Biochemistry, Faculty of Medicine , Acibadem Mehmet Ali Aydinlar University , Istanbul 34752 , Turkey. ^[5]

关键词 5xFAD Alzheimer’s disease MALDI imaging mass spectrometry amyloid plaques dentate gyrus gangliosides monosialogangliosides neurogenesis sialic acid