首页> Scientific reports> Increase in negative charge of <sup>68</sup>Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules.

Increase in negative charge of <sup>68</sup>Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules.

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第一作者： Sara S,Rinne

第一单位： Department of Medicinal Chemistry, Uppsala University, 751 23, Uppsala, Sweden.

作者： Sara S,Rinne ^[1] ; Charles,Dahlsson Leitao ^[2] ; Joshua,Gentry ^[1] ; Bogdan,Mitran ^[1] ; Ayman,Abouzayed ^[1] ; Vladimir,Tolmachev ^[3] ; Stefan,Ståhl ^[2] ; John,Löfblom ^[2] ; Anna,Orlova ^[4]

作者单位： Department of Medicinal Chemistry, Uppsala University, 751 23, Uppsala, Sweden. ^[1] Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, 106 91, Stockholm, Sweden. ^[2] Department of Immunology, Genetics and Pathology, Uppsala University, 751 85, Uppsala, Sweden. ^[3] Department of Medicinal Chemistry, Uppsala University, 751 23, Uppsala, Sweden. anna.orlova@ilk.uu.se.;Science for Life Laboratory, Uppsala University, 751 23, Uppsala, Sweden. anna.orlova@ilk.uu.se. ^[4]