A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.

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第一作者： Beatrice,Cubitt

第一单位： Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, 92037, USA.

作者： Beatrice,Cubitt ^[1] ; Emilio,Ortiz-Riano ^[2] ; Benson Yh,Cheng ^[2] ; Yu-Jin,Kim ^[1] ; Charles D,Yeh ^[3] ; Catherine Z,Chen ^[3] ; N O E,Southall ^[3] ; Wei,Zheng ^[3] ; Luis,Martinez-Sobrido ^[2] ; Juan C,de la Torre ^[4]

作者单位： Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, 92037, USA. ^[1] Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, 14642, USA. ^[2] National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, 20892, USA. ^[3] Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, 92037, USA. Electronic address: juanct@scripps.edu. ^[4]

主题词动物(Animals);抗病毒药(Antiviral Agents);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物评价, 临床前(Drug Evaluation, Preclinical);基因表达(Gene Expression);遗传工程(Genetic Engineering);HEK293细胞(HEK293 Cells);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);拉沙病毒(Lassa virus);RNA干扰(RNA Interference);结果可重复性(Reproducibility of Results);核糖核蛋白类(Ribonucleoproteins);小分子化合物库(Small Molecule Libraries);Vero细胞(Vero Cells);病毒蛋白质类(Viral Proteins)

DOI 10.1016/j.antiviral.2019.104667

PMID 31786250

发布时间 2024-07-27

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Antiviral research

2020年173卷

104667页

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A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.

Antiviral research

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Antiviral research

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A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.

Antiviral research

相似文献

Antiviral research

相关期刊

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