Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking.
作者:
主题词
碱基序列(Base Sequence);DNA(DNA);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA断裂, 单链(DNA Breaks, Single-Stranded);脱氧核糖核酸酶Ⅰ(Deoxyribonuclease I);内切核酸酶类(Endonucleases);基因打靶(Gene Targeting);基因组(Genome);人类(Humans);突变(Mutation)
DOI
10.1093/nar/gkz1121
PMID
31799604
发布时间
2024-03-27
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Nucleic acids research
974-995页
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