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首页> Cell death & disease> Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck.

Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck.

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作者： Rachel J,Carter ^[1] ; Mateus,Milani ^[2] ; Michael,Butterworth ^[2] ; Ahoud,Alotibi ^[2] ; Nicholas,Harper ^[2] ; Govindaraju,Yedida ^[3] ; Georgia,Greaves ^[2] ; Aoula,Al-Zebeeby ^[2] ; Andrea L,Jorgensen ^[2] ; Andrew G,Schache ^[4] ; Janet M,Risk ^[1] ; Richard J,Shaw ^[1] ; Terry M,Jones ^[1] ; Joseph J,Sacco ^[1] ; Adam,Hurlstone ^[1] ; Gerald M,Cohen ^[5] ; Shankar,Varadarajan ^[1]

作者单位： Liverpool Head and Neck Centre, Liverpool, L69 3GE, UK. ^[1] Department of Molecular and Clinical Cancer Medicine, Liverpool, L69 3GE, UK. ^[2] Department of Molecular and Clinical Pharmacology, Liverpool, L69 3GE, UK. ^[3] Department of Biostatistics, University of Liverpool, Liverpool, L69 3GE, UK. ^[4] Faculty of Biology, Medicine and Health, Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, M13 9PT, UK. ^[5] Liverpool Head and Neck Centre, Liverpool, L69 3GE, UK. svar@liverpool.ac.uk. ^[6] Department of Molecular and Clinical Cancer Medicine, Liverpool, L69 3GE, UK. svar@liverpool.ac.uk. ^[7] Department of Molecular and Clinical Pharmacology, Liverpool, L69 3GE, UK. svar@liverpool.ac.uk. ^[8]

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);顺铂(Cisplatin);女(雌)性(Female);人类(Humans);Kaplan-Meiers评估(Kaplan-Meier Estimate);男(雄)性(Male);中年人(Middle Aged);肿瘤蛋白质类(Neoplasm Proteins);肽碎片(Peptide Fragments);原癌基因蛋白质类(Proto-Oncogene Proteins);治疗结果(Treatment Outcome);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);斑马鱼(Zebrafish)

DOI 10.1038/s41419-019-2150-8

PMID 31801952

发布时间 2021-01-10

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Cell death & disease

Cell death & disease

2019年10卷12期

912页

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