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Predictive impact of rare genomic copy number variations in siblings of individuals with autism spectrum disorders.

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作者: L,D'Abate [1] ; S,Walker [2] ; R K C,Yuen [1] ; K,Tammimies [1] ; J A,Buchanan [2] ; R W,Davies [1] ; B,Thiruvahindrapuram [3] ; J,Wei [4] ; J,Brian [1] ; S E,Bryson [1] ; K,Dobkins [1] ; J,Howe [1] ; R,Landa [5] ; J,Leef [6] ; D,Messinger [7] ; S,Ozonoff [1] ; I M,Smith [8] ; W L,Stone [5] ; Z E,Warren [9] ; G,Young [10] ; L,Zwaigenbaum [6] ; S W,Scherer [11]
作者单位: The Centre for Applied Genomics, Genetics, and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada. [1] Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. [2] Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Department of Women's and Children's Health, Stockholm, Sweden. [3] Center for Psychiatry Research, Region Stockholm, Stockholm, Sweden. [4] Autism Research Centre, Bloorview Research Institute and University of Toronto, Toronto, ON, Canada. [5] Autism Research Centre, IWK Health Centre and Dalhousie University, Halifax, NS, Canada. [6] Department of Psychology, UC San Diego, La Jolla, CA, USA. [7] Center for Autism and Related Disorders, Kennedy Krieger Institute, Baltimore, MD, USA. [8] Department of Psychology, University of Miami, Coral Gables, FL, USA. [9] MIND Institute, Department of Psychiatry, UC Davis, Davis, CA, USA. [10] Department of Psychology, University of Washington, Seattle, WA, USA. [11] Vanderbilt Kennedy Center Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt Kennedy Centre, Nashville, TN, USA. [12] Autism Research Centre, University of Alberta, Edmonton, AB, Canada. [13] The Centre for Applied Genomics, Genetics, and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada. stephen.scherer@sickkids.ca. [14] Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. stephen.scherer@sickkids.ca. [15] McLaughlin Centre, University of Toronto, Toronto, ON, Canada. stephen.scherer@sickkids.ca. [16]
DOI 10.1038/s41467-019-13380-2
PMID 31801954
发布时间 2021-01-10
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