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Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation.

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作者单位: Translational and Clinical Research Institute, Newcastle University, Newcastle, UK. [1] The Wellcome-Wolfson Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK; Regional Intensive Care Unit, The Royal Hospitals, Belfast, UK. [2] Anaesthesia, Critical Care and Pain Medicine, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, UK; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK. [3] Usher Institute, University of Edinburgh, Edinburgh, UK. [4] Division of Anaesthesia, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. [5] Department of Cancer and Surgery, Imperial College London, London, UK. [6] Division of Infection Immunity and Respiratory Medicine, Manchester National Institute for Health Research Biomedical Research Centre, University of Manchester, Manchester, UK. [7] Integrated Critical Care Unit, Sunderland Royal Hospital, City Hospitals Sunderland NHS Foundation Trust, Sunderland, UK. [8] Warwick Medical School, University of Warwick, Coventry, UK; Intensive Care Unit, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. [9] The Wellcome-Wolfson Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK. [10] Integrated Critical Care Unit, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK. [11] Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK. [12] Intensive Care Unit, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK. [13] Intensive Care Unit, Western General Hospital, Edinburgh, UK. [14] Translational and Clinical Research Institute, Newcastle University, Newcastle, UK; Integrated Critical Care Unit, Sunderland Royal Hospital, City Hospitals Sunderland NHS Foundation Trust, Sunderland, UK. [15] Northern Ireland Clinical Trials Unit, The Royal Hospitals, Belfast, UK. [16] Intensive Care Unit, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, UK. [17] Intensive Care Unit, Countess of Chester NHS Foundation Trust, Chester, UK. [18] Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK. [19] Intensive Care Unit, University Hospital Coventry, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK. [20] Intensive Care Unit, Northumbria Specialist Emergency Care Hospital, Cramlington, UK. [21] Intensive Care Unit, Preston Royal Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK. [22] Intensive Care Unit, Sandwell General Hospital, Sandwell and West Birmingham Hospitals NHS Trust, West Bromwich, UK. [23] Intensive Care Unit, James Cook University Hospital, South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK. [24] Intensive Care Unit, Queen Elizabeth Hospital, Gateshead NHS Foundation Trust, Gateshead, UK. [25] Intensive Care Unit, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK. [26] Becton Dickinson Biosciences Europe, Erembodegem, Belgium. [27] National Institute for Health Research Newcastle In Vitro Diagnostics Cooperative, Newcastle University, Newcastle, UK. [28] Newcastle Clinical Trials Unit, Newcastle University, Newcastle, UK. [29] Translational and Clinical Research Institute, Newcastle University, Newcastle, UK; National Institute for Health Research Newcastle In Vitro Diagnostics Cooperative, Newcastle University, Newcastle, UK. Electronic address: j.simpson@ncl.ac.uk. [30]
DOI 10.1016/S2213-2600(19)30367-4
PMID 31810865
发布时间 2024-02-07
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The Lancet. Respiratory medicine

The Lancet. Respiratory medicine

2020年8卷2期

182-191页

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