首页> Clinical cancer research : an official journal of the American Association for Cancer Research> Efficacy and Safety of Dabrafenib in Pediatric Patients with <i>BRAF</i> V600 Mutation-Positive Relapsed or Refractory Low-Grade Glioma: Results from a Phase I/IIa Study.

Efficacy and Safety of Dabrafenib in Pediatric Patients with <i>BRAF</i> V600 Mutation-Positive Relapsed or Refractory Low-Grade Glioma: Results from a Phase I/IIa Study.

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第一作者： Darren R,Hargrave

第一单位： Pediatric Oncology Unit, UCL Great Ormond Street Institute of Child Health, London, United Kingdom. darren.hargrave@nhs.net.

作者： Darren R,Hargrave ^[1] ; Eric,Bouffet ^[2] ; Uri,Tabori ^[3] ; Alberto,Broniscer ^[4] ; Kenneth J,Cohen ^[5] ; Jordan R,Hansford ^[6] ; Birgit,Geoerger ^[7] ; Pooja,Hingorani ^[8] ; Ira J,Dunkel ^[9] ; Mark W,Russo ^[10] ; Lillian,Tseng ^[10] ; Kohinoor,Dasgupta ^[11] ; Eduard,Gasal ^[10] ; James A,Whitlock ^[2] ; Mark W,Kieran ^[12]

作者单位： Pediatric Oncology Unit, UCL Great Ormond Street Institute of Child Health, London, United Kingdom. darren.hargrave@nhs.net. ^[1] Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. ^[2] Arthur and Sonia Labatt Brain Tumor Research Center, Division of Hematology/Oncology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. ^[3] Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee. ^[4] The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Division of Pediatric Oncology, Baltimore, Maryland. ^[5] Department of Pediatrics, The Royal Children's Hospital, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Victoria, Australia. ^[6] Department of Childhood and Adolescent Oncology, Gustave Roussy Cancer Center, Université Paris-Saclay, Villejuif, France. ^[7] Phoenix Children's Hospital, Center for Cancer and Blood Disorders, Phoenix, Arizona. ^[8] Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York. ^[9] Novartis Pharmaceuticals Corporation, East Hanover, New Jersey. ^[10] Novartis Healthcare Pvt. Ltd., Hyderabad, India. ^[11] Harvard Medical School, Boston Children's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts. ^[12]