Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcoma.

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作者： Konrad,Steinestel ^[1] ; Marcel,Trautmann ^[2] ; Esther-Pia,Jansen ^[1] ; Uta,Dirksen ^[3] ; Jan,Rehkämper ^[1] ; Jan-Henrik,Mikesch ^[4] ; Julia S,Gerke ^[5] ; Martin F,Orth ^[6] ; Giuseppina,Sannino ^[7] ; Maria-Francisca,Arteaga ^[7] ; Claudia,Rossig ^[7] ; Eva,Wardelmann ^[6] ; Thomas G P,Grünewald ^[8] ; Wolfgang,Hartmann ^[1]

作者单位： Gerhard Domagk Institute of Pathology, University Hospital Münster, Germany. ^[1] Institute of Pathology and Molecular Pathology, Bundeswehrkrankenhaus Ulm, Germany. ^[2] Division of Translational Pathology, Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Germany. ^[3] Pediatrics III, West German Cancer Centre, University Hospital Essen, Germany. ^[4] Institute of Pathology, University Hospital Cologne, Germany. ^[5] Department of Medicine A, University Hospital Münster, Germany. ^[6] Max Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Germany. ^[7] Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Germany. ^[8] German Cancer Consortium (DKTK), Partner Site Munich, Germany. ^[9] German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[10] Institute of Pathology, Faculty of Medicine, LMU Munich, Germany. ^[11]

关键词 Ewing sarcoma cytoskeleton focal adhesion kinase metastasis migration