Novel study design to assess the efficacy and tolerability of antiseizure medications for focal-onset seizures in infants and young children: A consensus document from the regulatory task force and the pediatric commission of the International League against Epilepsy (ILAE), in collaboration with the Pediatric Epilepsy Research Consortium (PERC).

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第一作者： Stéphane,Auvin

第一单位： Department of Pediatric Neurology AP-HP Robert-Debré University Hospital CRMR Epilepsies Rares Paris France.

作者： Stéphane,Auvin ^[1] ; Jacqueline,French ^[2] ; Denis,Dlugos ^[3] ; Kelly G,Knupp ^[4] ; Emilio,Perucca ^[5] ; Alexis,Arzimanoglou ^[6] ; Ed,Whalen ^[7] ; Renée A,Shellhaas ^[8]

作者单位： Department of Pediatric Neurology AP-HP Robert-Debré University Hospital CRMR Epilepsies Rares Paris France. ^[1] Université de Paris INSERM U1141 Paris France. ^[2] NYU Langone School of Medicine New York NY USA. ^[3] Division of Neurology Children's Hospital of Philadelphia (CHOP) Philadelphia PA USA. ^[4] Departments of Neurology and Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia PA USA. ^[5] Department of Pediatrics and Neurology University of Colorado Aurora CO USA. ^[6] Department of Internal Medicine and Therapeutics Member of the ERN EpiCARE University of Pavia and IRCCS Mondino Foundation Pavia Italy. ^[7] Department of Clinical Pediatric Epileptology and Functional Neurology Member of the ERN EpiCARE University Hospitals of Lyon (HCL) Lyon France. ^[8] Global Biometrics and Data Management Pfizer Inc New York NY USA. ^[9] Division of Pediatric Neurology Department of Pediatrics Michigan Medicine Ann Arbor MI USA. ^[10]

关键词 antiseizure drugs children clinical trials drug development infants

DOI 10.1002/epi4.12356

PMID 31819909

发布时间 2023-10-20

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