Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2.-论文-万方医学网

作者： Subhankar,Mukhopadhyay ^[1] ; Eva,Heinz ^[2] ; Immacolata,Porreca ^[1] ; Kaur,Alasoo ^[1] ; Amy,Yeung ^[1] ; Huei-Ting,Yang ^[1] ; Tobias,Schwerd ^[3] ; Jessica L,Forbester ^[4] ; Christine,Hale ^[3] ; Chukwuma A,Agu ^[5] ; Yoon Ha,Choi ^[1] ; Julia,Rodrigues ^[6] ; Melania,Capitani ^[1] ; Luke,Jostins-Dean ^[1] ; David C,Thomas ^[1] ; Simon,Travis ^[1] ; Daniel,Gaffney ^[3] ; William C,Skarnes ^[7] ; Nicholas,Thomson ^[8] ; Holm H,Uhlig ^[3] ; Gordon,Dougan ^[1] ; Fiona,Powrie ^[1]

作者单位： Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK. ^[1] Medical Research Council Centre for Transplantation, Peter Gorer Department of Immunobiology, King's College London, London, UK. ^[2] Translational Gastroenterology Unit, Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK. ^[3] Swiss Precision Dignostics Development Company Limited, Bedford, UK. ^[4] Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany. ^[5] Division of Infection and Immunity, Cardiff University, Cardiff, UK. ^[6] The Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK. ^[7] Department of Medicine, University of Cambridge, University of Cambridge School of Clinical Medicine, Cambridge, UK. ^[8] The Jackson Laboratory for Genomic Medicine, Farmington, CT. ^[9] Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, UK. ^[10] Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK. ^[11]

主题词细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);地诺前列酮(Dinoprostone);女(雌)性(Female);基因敲除技术(Gene Knockout Techniques);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);炎症(Inflammation);炎性肠疾病(Inflammatory Bowel Diseases);白细胞介素10(Interleukin-10);白细胞介素10受体α亚单位(Interleukin-10 Receptor alpha Subunit);白细胞介素10受体β亚单位(Interleukin-10 Receptor beta Subunit);脂多糖类(Lipopolysaccharides);巨噬细胞活化(Macrophage Activation);巨噬细胞(Macrophages);突变(Mutation);磷酰化(Phosphorylation);STAT3转录因子(STAT3 Transcription Factor);鼠伤寒沙门菌(Salmonella typhimurium);信号传导(Signal Transduction)

DOI 10.1084/jem.20180649

PMID 31819956

发布时间 2021-01-10

检索历史清除

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2.

The Journal of experimental medicine

相似文献

The Journal of experimental medicine

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2.

The Journal of experimental medicine

相似文献

The Journal of experimental medicine

相关期刊

检索历史清除