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Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma.

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作者单位: Immunology, Microenvironment and Metastasis, The Wistar Institute, Philadelphia, PA, 19104, U.S.A.; Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA. Electronic address: websterm@mlhs.org. [1] Immunology, Microenvironment and Metastasis, The Wistar Institute, Philadelphia, PA, 19104, U.S.A. [2] Immunology, Microenvironment and Metastasis, The Wistar Institute, Philadelphia, PA, 19104, U.S.A.; University of the Sciences, Philadelphia, PA 19104, USA. [3] Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA 19104, USA. [4] Bioinformatics, The Wistar Institute, Philadelphia, PA 19104, USA. [5] Immunology, Microenvironment and Metastasis, The Wistar Institute, Philadelphia, PA, 19104, U.S.A.; Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA 19104, USA. [6] Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA 19104, USA; Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. [7] Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. [8] Fox Chase Cancer Center, Philadelphia, PA 19111, USA. [9] State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, Zhejiang 310003, China. [10] Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Tara Miller Melanoma Center at Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. [11] Immunology, Microenvironment and Metastasis, The Wistar Institute, Philadelphia, PA, 19104, U.S.A.; Department of Biochemistry and Molecular Biology, Johns Hopkins School of Public Health and Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA. Electronic address: aweerara1@jhu.edu. [12]
DOI 10.1016/j.molcel.2019.11.009
PMID 31836388
发布时间 2021-02-06
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