Reduced activated regulatory T cells and imbalance of Th17/activated Treg cells marks renal involvement in ANCA-associated vasculitis.

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作者： Yanlin,Wang ^[1] ; Shulan,Zhang ^[2] ; Na,Zhang ^[1] ; Min,Feng ^[1] ; Zhaojun,Liang ^[1] ; Xiangcong,Zhao ^[3] ; Chong,Gao ^[4] ; Yan,Qin ^[1] ; Yanyao,Wu ^[1] ; Guangying,Liu ^[3] ; Jinfang,Zhao ^[5] ; Hui,Guo ^[6] ; Jing,Luo ^[7]

作者单位： Shanxi Medical University, Taiyuan, Shanxi 030001, China. ^[1] Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China. ^[2] Division of Rheumatology, Department of Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China. ^[3] Department of Pathology,Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ^[4] Department of Medical Statistics, Shanxi Medical University, Taiyuan, China. ^[5] Division of Nephrology, Department of Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China; Division of Nephrology, Department of Medicine, Shenzhen Baoan Shiyan People's Hospital, Shenzhen, Guangdong 518005, China. Electronic address: ghty966@126.com. ^[6] Division of Rheumatology, Department of Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China. Electronic address: ljty966@hotmail.com. ^[7]

关键词 ANCA-associated vasculitis T-cell abnormality Th17 cells Treg subsets