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Molecular phenotyping and image-guided surgical treatment of melanoma using spectrally distinct ultrasmall core-shell silica nanoparticles.

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第一作者： Feng,Chen

第一单位： Department of Radiology, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA.

作者： Feng,Chen ^[1] ; Brian,Madajewski ^[1] ; Kai,Ma ^[2] ; Daniella,Karassawa Zanoni ^[3] ; Hilda,Stambuk ^[1] ; Melik Z,Turker ^[2] ; Sébastien,Monette ^[4] ; Li,Zhang ^[1] ; Barney,Yoo ^[1] ; Peiming,Chen ^[1] ; Richard J C,Meester ^[5] ; Sander,de Jonge ^[5] ; Pablo,Montero ^[3] ; Evan,Phillips ^[1] ; Thomas P,Quinn ^[6] ; Mithat,Gönen ^[7] ; Sonia,Sequeira ^[8] ; Elisa,de Stanchina ^[9] ; Pat,Zanzonico ^[10] ; Ulrich,Wiesner ^[2] ; Snehal G,Patel ^[3] ; Michelle S,Bradbury ^[11]

作者单位： Department of Radiology, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA. ^[1] Department of Materials Science & Engineering, Cornell University, Ithaca, NY 14853, USA. ^[2] Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ^[3] Laboratory of Comparative Pathology, Center of Comparative Medicine and Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ^[4] Quest Medical Imaging B.V., NL-1775PW, Middenmeer, Netherlands. ^[5] Department of Biochemistry, University of Missouri, Columbia, MO 65211, USA.;Harry S Truman Veterans' Hospital, Columbia, MO 65201, USA. ^[6] Department of Epidemiology and Biostatistics, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA. ^[7] Research and Technology Management, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA. ^[8] Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ^[9] Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ^[10] Department of Radiology, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA.;Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA. ^[11]

医学主题词动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);淋巴结(Lymph Nodes);淋巴转移(Lymphatic Metastasis);黑色素瘤(Melanoma);小鼠(Mice);纳米粒子(Nanoparticles);粒子大小(Particle Size);表型(Phenotype);前哨淋巴结活组织检查(Sentinel Lymph Node Biopsy);二氧化硅(Silicon Dioxide);外科手术, 计算机辅助(Surgery, Computer-Assisted);猪(Swine);猪, 雏型(Swine, Miniature)

DOI 10.1126/sciadv.aax5208

PMID 31840066

发布时间 2024-04-22

基金项目

P30 CA008748/CA/NCI NIH HHS/United States U54 CA199081/CA/NCI NIH HHS/United States

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Molecular phenotyping and image-guided surgical treatment of melanoma using spectrally distinct ultrasmall core-shell silica nanoparticles.

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Molecular phenotyping and image-guided surgical treatment of melanoma using spectrally distinct ultrasmall core-shell silica nanoparticles.

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