换一批High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.
第一作者：
Lucie,Abeler-Dörner
第一单位：
Department of Immunobiology, King's College London, London, UK.
作者：
Lucie,Abeler-Dörner [1]
;
Adam G,Laing [2]
;
Anna,Lorenc [2]
;
Dmitry S,Ushakov [2]
;
Simon,Clare [3]
;
Anneliese O,Speak [3]
;
Maria A,Duque-Correa [3]
;
Jacqueline K,White [3]
;
Ramiro,Ramirez-Solis [3]
;
Namita,Saran [1]
;
Katherine R,Bull [4]
;
Belén,Morón [5]
;
Jua,Iwasaki [6]
;
Philippa R,Barton [7]
;
Susana,Caetano [8]
;
Keng I,Hng [1]
;
Emma,Cambridge [3]
;
Simon,Forman [9]
;
Tanya L,Crockford [4]
;
Mark,Griffiths [3]
;
Leanne,Kane [3]
;
Katherine,Harcourt [3]
;
Cordelia,Brandt [3]
;
George,Notley [3]
;
Kolawole O,Babalola [10]
;
Jonathan,Warren [10]
;
Jeremy C,Mason [10]
;
Amrutha,Meeniga [10]
;
Natasha A,Karp [11]
;
David,Melvin [3]
;
Eleanor,Cawthorne [4]
;
Brian,Weinrick [12]
;
Albina,Rahim [13]
;
Sibyl,Drissler [13]
;
Justin,Meskas [13]
;
Alice,Yue [13]
;
Markus,Lux [13]
;
George X,Song-Zhao [5]
;
Anna,Chan [1]
;
Carmen,Ballesteros Reviriego [3]
;
Johannes,Abeler [14]
;
Heather,Wilson [3]
;
Agnieszka,Przemska-Kosicka [1]
;
Matthew,Edmans [4]
;
Natasha,Strevens [3]
;
Markus,Pasztorek [15]
;
Terrence F,Meehan [10]
;
Fiona,Powrie [16]
;
Ryan,Brinkman [17]
;
Gordon,Dougan [3]
;
William,Jacobs [12]
;
Clare M,Lloyd [6]
;
Richard J,Cornall [4]
;
Kevin J,Maloy [18]
;
Richard K,Grencis [9]
;
Gillian M,Griffiths [7]
;
David J,Adams [3]
;
Adrian C,Hayday [19]
作者单位：
Department of Immunobiology, King's College London, London, UK.
[1]
Department of Immunobiology, King's College London, London, UK.;The Francis Crick Institute, London, UK.
[2]
Wellcome Sanger Institute, Hinxton, UK.
[3]
MRC Human Immunology Unit, University of Oxford, Oxford, UK.
[4]
Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
[5]
National Heart and Lung Institute, Imperial College London, London, UK.
[6]
Cambridge Institute of Medical Research, University of Cambridge, Cambridge, UK.
[7]
Department of Immunobiology, King's College London, London, UK.;Wellcome Sanger Institute, Hinxton, UK.
[8]
Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
[9]
European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK.
[10]
Data Sciences & Quantitative Biology, Discovery Sciences, R&D Biopharmaceuticals, AstraZeneca, Cambridge, UK.
[11]
Department of Microbiology and Immunology, Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
[12]
Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada.
[13]
Department of Economics, University of Oxford, Oxford, UK.
[14]
Department of Immunobiology, King's College London, London, UK.;Department of Biomedical Science, University of Applied Sciences FH Campus Wien, Vienna, Austria.
[15]
The Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
[16]
Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada.;Department of Bioinformatics, University of British Columbia, Vancouver, BC, Canada.
[17]
Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UK.
[18]
Department of Immunobiology, King's College London, London, UK. adrian.hayday@kcl.ac.uk.;The Francis Crick Institute, London, UK. adrian.hayday@kcl.ac.uk.
[19]
医学主题词
动物(Animals);柠檬酸杆菌属(Citrobacter);肠杆菌科感染(Enterobacteriaceae Infections);女(雌)性(Female);遗传变异(Genetic Variation);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);免疫表型分型(Immunophenotyping);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);模型, 动物(Models, Animal);沙门菌属(Salmonella);沙门菌感染(Salmonella Infections)
DOI
10.1038/s41590-019-0549-0
PMID
31844327
发布时间
2025-05-30
- 浏览5
Nature immunology
Nature immunology
86-100页
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