SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.

导出 OA

翻译打印收藏纠错

第一作者： Shoshana,Naiman

第一单位： Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 5290002, Israel.

作者： Shoshana,Naiman ^[1] ; Frank K,Huynh ^[2] ; Reuven,Gil ^[1] ; Yair,Glick ^[1] ; Yael,Shahar ^[1] ; Noga,Touitou ^[1] ; Liat,Nahum ^[1] ; Matan Y,Avivi ^[1] ; Asael,Roichman ^[1] ; Yariv,Kanfi ^[1] ; Asaf A,Gertler ^[1] ; Tirza,Doniger ^[1] ; Olga R,Ilkayeva ^[3] ; Ifat,Abramovich ^[4] ; Orly,Yaron ^[1] ; Batia,Lerrer ^[1] ; Eyal,Gottlieb ^[4] ; Robert A,Harris ^[5] ; Doron,Gerber ^[6] ; Matthew D,Hirschey ^[3] ; Haim Y,Cohen ^[7]

作者单位： Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 5290002, Israel. ^[1] Department of Biological Sciences, San Jose State University, San Jose, CA 95192, USA; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27710, USA; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, NC 27710, USA. ^[2] Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27710, USA; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, NC 27710, USA. ^[3] The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, 1 Efron Street, Bat Galim, Haifa, Israel. ^[4] Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA. ^[5] Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 5290002, Israel; Bar Ilan Institute for Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel. ^[6] Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 5290002, Israel. Electronic address: haim.cohen@biu.ac.il. ^[7]

关键词 PPARα SIRT6 beta-oxidation deacetylase fasting liver