换一批
换一批Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
第一作者：
Madeline H,Kowalski
第一单位：
Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
作者：
Madeline H,Kowalski [1]
;
Huijun,Qian [2]
;
Ziyi,Hou [3]
;
Jonathan D,Rosen [1]
;
Amanda L,Tapia [1]
;
Yue,Shan [1]
;
Deepti,Jain [4]
;
Maria,Argos [5]
;
Donna K,Arnett [6]
;
Christy,Avery [7]
;
Kathleen C,Barnes [8]
;
Lewis C,Becker [9]
;
Stephanie A,Bien [10]
;
Joshua C,Bis [11]
;
John,Blangero [12]
;
Eric,Boerwinkle [13]
;
Donald W,Bowden [14]
;
Steve,Buyske [15]
;
Jianwen,Cai [16]
;
Michael H,Cho [17]
;
Seung Hoan,Choi [18]
;
Hélène,Choquet [19]
;
L Adrienne,Cupples [20]
;
Mary,Cushman [21]
;
Michelle,Daya [8]
;
Paul S,de Vries [22]
;
Patrick T,Ellinor [23]
;
Nauder,Faraday [9]
;
Myriam,Fornage [24]
;
Stacey,Gabriel [25]
;
Santhi K,Ganesh [26]
;
Misa,Graff [7]
;
Namrata,Gupta [25]
;
Jiang,He [27]
;
Susan R,Heckbert [28]
;
Bertha,Hidalgo [29]
;
Chani J,Hodonsky [7]
;
Marguerite R,Irvin [29]
;
Andrew D,Johnson [30]
;
Eric,Jorgenson [19]
;
Robert,Kaplan [31]
;
Sharon L R,Kardia [32]
;
Tanika N,Kelly [27]
;
Charles,Kooperberg [10]
;
Jessica A,Lasky-Su [17]
;
Ruth J F,Loos [33]
;
Steven A,Lubitz [23]
;
Rasika A,Mathias [9]
;
Caitlin P,McHugh [4]
;
Courtney,Montgomery [34]
;
Jee-Young,Moon [31]
;
Alanna C,Morrison [22]
;
Nicholette D,Palmer [14]
;
Nathan,Pankratz [35]
;
George J,Papanicolaou [36]
;
Juan M,Peralta [12]
;
Patricia A,Peyser [32]
;
Stephen S,Rich [37]
;
Jerome I,Rotter [38]
;
Edwin K,Silverman [17]
;
Jennifer A,Smith [32]
;
Nicholas L,Smith [39]
;
Kent D,Taylor [38]
;
Timothy A,Thornton [4]
;
Hemant K,Tiwari [40]
;
Russell P,Tracy [41]
;
Tao,Wang [42]
;
Scott T,Weiss [17]
;
Lu-Chen,Weng [18]
;
Kerri L,Wiggins [11]
;
James G,Wilson [43]
;
Lisa R,Yanek [9]
;
Sebastian,Zöllner [44]
;
Kari E,North [45]
;
Paul L,Auer [46]
;
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium [47]
;
TOPMed Hematology & Hemostasis Working Group [48]
;
Laura M,Raffield [49]
;
Alexander P,Reiner ;
Yun,Li
作者单位：
Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
[1]
Department of Statistics and Operation Research, University of North Carolina, Chapel Hill, North Carolina, United States of America.
[2]
Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America.
[3]
Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
[4]
Division of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, Illinois, United States of America.
[5]
College of Public Health, University of Kentucky, Lexington, Kentucky, United States of America.
[6]
Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
[7]
Department of Medicine, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, United States of America.
[8]
GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
[9]
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
[10]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America.
[11]
Department of Human Genetics and South Texas Diabetes Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas, United States of America.
[12]
Human Genome Sequencing Center, University of Texas Health Science Center at Houston; Baylor College of Medicine, Houston, Texas, United States of America.;Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
[13]
Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
[14]
Department of Statistics, Rutgers University, Piscataway, New Jersey, United States of America.
[15]
Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
[16]
Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.;Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
[17]
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
[18]
Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America.
[19]
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.;Framingham Heart Study, Framingham, Massachusetts, United States of America.
[20]
Departments of Medicine & Pathology, Larner College of Medicine, University of Vermont, Colchester, Vermont, United States of America.
[21]
Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
[22]
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.;Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
[23]
School of Public Health, The University of Texas Health Science Center, Houston, Texas, United States of America.
[24]
Genomics Platform, Broad Institute, Cambridge, Massachusetts, United States of America.
[25]
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.;Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
[26]
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Los Angeles, United States of America.
[27]
Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.;Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, Washington, United States of America.
[28]
Department of Epidemiology, Ryals School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
[29]
Framingham Heart Study, Framingham, Massachusetts, United States of America.;Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, Massachusetts, United States of America.
[30]
Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America.
[31]
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.
[32]
The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.;The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
[33]
Department of Genes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.
[34]
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, United States of America.
[35]
National Heart, Lung, and Blood Institute, Division of Cardiovascular Sciences, PPSP/EB, NIH, Bethesda, Maryland, United States of America.
[36]
Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.
[37]
The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
[38]
Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.;Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, Washington, United States of America.;Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, Washington, United States of America.
[39]
Department of Biostatistics, Ryals School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
[40]
Departments of Pathology & Laboratory Medicine and Biochemistry, Larrner College of Medicine, University of Vermont, Colchester, Vermont, United States of America.
[41]
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America.
[42]
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
[43]
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America.;Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, United States of America.
[44]
Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.;Carolina Center of Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
[45]
Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America.
[46]
Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.
[47]
Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.
[48]
Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America.;Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.;Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States of America.
[49]
主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);计算生物学(Computational Biology);数据库, 遗传学(Databases, Genetic);女(雌)性(Female);基因频率(Gene Frequency);疾病遗传易感性(Genetic Predisposition to Disease);遗传学, 群体(Genetics, Population);全基因组关联研究(Genome-Wide Association Study);人类(Humans);连锁不平衡(Linkage Disequilibrium);男(雄)性(Male);中年人(Middle Aged);美国(United States);β珠蛋白类(beta-Globins)
DOI
10.1371/journal.pgen.1008500
PMID
31869403
发布时间
2024-12-07
- 浏览3
PLoS genetics
PLoS genetics
e1008500页
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