Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.

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第一作者： Chiara,Baccin

第一单位： Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

作者： Chiara,Baccin ^[1] ; Jude,Al-Sabah ^[2] ; Lars,Velten ^[3] ; Patrick M,Helbling ^[4] ; Florian,Grünschläger ^[5] ; Pablo,Hernández-Malmierca ^[6] ; César,Nombela-Arrieta ^[7] ; Lars M,Steinmetz ^[3] ; Andreas,Trumpp ^[4] ; Simon,Haas ^[3]

作者单位： Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. ^[1] Faculty of Biosciences, Joint PhD degree from EMBL and Heidelberg University, Heidelberg, Germany. ^[2] Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany. ^[3] Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany. ^[4] Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. lars.velten@embl.de. ^[5] Center for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain. lars.velten@embl.de. ^[6] Department of Medical Oncology and Hematology, University Hospital and University of Zürich, Zürich, Switzerland. ^[7] Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. larsms@embl.de. ^[8] Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. larsms@embl.de. ^[9] Stanford Genome Technology Center, Palo Alto, CA, USA. larsms@embl.de. ^[10] Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany. a.trumpp@dkfz-heidelberg.de. ^[11] Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany. a.trumpp@dkfz-heidelberg.de. ^[12] German Cancer Consortium (DKTK), Heidelberg, Germany. a.trumpp@dkfz-heidelberg.de. ^[13] Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany. s.haas@dkfz-heidelberg.de. ^[14] Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany. s.haas@dkfz-heidelberg.de. ^[15]