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首页> International journal of biological macromolecules> An insight into the complete biophysical and biochemical characterization of novel class A beta-lactamase (Bla1) from Bacillus anthracis.

An insight into the complete biophysical and biochemical characterization of novel class A beta-lactamase (Bla1) from Bacillus anthracis.

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作者： Sourya,Bhattacharya ^[1] ; Vivek,Junghare ^[1] ; Niteesh Kumar,Pandey ^[1] ; Debashish,Ghosh ^[2] ; Hirak,Patra ^[3] ; Saugata,Hazra ^[4]

作者单位： Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, India. ^[1] Biotechnology Conversion Area, Bio Fuels Division, CSIR-Indian Institute of Petroleum, Dehradun, Uttarakhand 248005, India. ^[2] Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK. ^[3] Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, India; Centre of Nanotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, India. Electronic address: saugata.iitk@gmail.com. ^[4]

关键词 Antimicrobial resistance Biochemical studies Biophysical characterization Catalytic divergence Minimum inhibitory concentration Molecular docking Molecular dynamics simulation Spectrophotometry techniques

主题词抗菌药(Anti-Bacterial Agents);炭疽芽孢杆菌(Bacillus anthracis);人类(Humans);动力学(Kinetics);微生物敏感性试验(Microbial Sensitivity Tests);分子动力学模拟(Molecular Dynamics Simulation);热力学(Thermodynamics);β-内酰胺酶类(beta-Lactamases)

DOI 10.1016/j.ijbiomac.2019.12.136

PMID 31874266

发布时间 2020-11-20

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International journal of biological macromolecules

510-526页

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