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Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis.

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第一作者： Kristina M,Harris

第一单位： Immune Tolerance Network, Bethesda, Maryland, USA.

作者： Kristina M,Harris ^[1] ; Noha,Lim ^[1] ; Paul,Lindau ^[2] ; Harlan,Robins ^[3] ; Linda M,Griffith ^[4] ; Richard A,Nash ^[5] ; Laurence A,Turka ^[6] ; Paolo A,Muraro ^[7]

作者单位： Immune Tolerance Network, Bethesda, Maryland, USA. ^[1] Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. ^[2] Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.;Adaptive Biotechnologies, Seattle, Washington, USA. ^[3] Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA. ^[4] Colorado Blood Cancer Institute, Presbyterian/St. Luke's, Denver, Colorado, USA. ^[5] Immune Tolerance Network, Bethesda, Maryland, USA.;Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[6] Department of Brain Sciences, Imperial College London, London, United Kingdom. ^[7]

关键词 Autoimmunity Hematopoietic stem cells Immunology Multiple sclerosis T-cell receptor

医学主题词 CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);造血干细胞移植(Hematopoietic Stem Cell Transplantation);人类(Humans);多发性硬化, 复发缓解性(Multiple Sclerosis, Relapsing-Remitting);T淋巴细胞(T-Lymphocytes);移植, 自体(Transplantation, Autologous)

DOI 10.1172/jci.insight.127655

PMID 31877116

发布时间 2020-11-20

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