Single Cell Mass Cytometry Revealed the Immunomodulatory Effect of Cisplatin Via Downregulation of Splenic CD44+, IL-17A+ MDSCs and Promotion of Circulating IFN-γ+ Myeloid Cells in the 4T1 Metastatic Breast Cancer Model.
作者:
主题词
动物(Animals);乳腺肿瘤(Breast Neoplasms);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);顺铂(Cisplatin);减量调节(Down-Regulation);内肽酶类(Endopeptidases);女(雌)性(Female);明胶酶类(Gelatinases);人类(Humans);免疫表型分型(Immunophenotyping);干扰素γ(Interferon-gamma);白细胞介素17(Interleukin-17);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);肿瘤细胞, 循环(Neoplastic Cells, Circulating);丝氨酸内肽酶类(Serine Endopeptidases);移植, 异种(Transplantation, Heterologous)
DOI
10.3390/ijms21010170
PMID
31881770
发布时间
2021-12-04
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