换一批
换一批Synthesis and biological evaluation of 4-arylcoumarins as potential anti-Alzheimer's disease agents.
第一作者：
Yinling,Yun
第一单位：
School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, Shandong, China; Institute of MateriaMedica, Shandong Academy of Medical Sciences, Jinan, Shandong, China; Key Laboratory for Biotech-Drugs Ministry of Health, Jinan, Shandong, China; Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Jinan, Shandong, China.
作者：
主题词
乙酰胆碱酯酶(Acetylcholinesterase);阿尔茨海默病(Alzheimer Disease);结合部位(Binding Sites);丁酰胆碱酯酶(Butyrylcholinesterase);胆碱酯酶抑制剂(Cholinesterase Inhibitors);香豆素类(Coumarins);人类(Humans);半数抑制浓度(Inhibitory Concentration 50);动力学(Kinetics);单胺氧化酶(Monoamine Oxidase);单胺氧化酶抑制剂(Monoamine Oxidase Inhibitors);蛋白质结构, 三级(Protein Structure, Tertiary);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bmcl.2019.126900
PMID
31882295
发布时间
2021-01-28
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