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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.

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作者单位: Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY 10016, USA. Electronic address: hua.zhang@nyulangone.org. [1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. [2] Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. [3] Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY 10016, USA. [4] S. Arthur Localio Laboratory, Department of Surgery, New York University School of Medicine, New York, NY 10016, USA. [5] Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA. [6] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. [7] Departments of Biology and Computer Science, Center for Genomics and Systems Biology, New York University, New York, NY 10010, USA. [8] Department of Pathology, New York University School of Medicine, New York, NY 10016, USA. [9] Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA. [10] Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. [11] Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia. [12] Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia. [13] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. [14] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA. Electronic address: nathanael_gray@dfci.harvard.edu. [15] Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY 10016, USA. Electronic address: kwok_kin.wong@nyulangone.org. [16]
DOI 10.1016/j.ccell.2019.11.003
PMID 31883968
发布时间 2022-12-07
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