Stochastic transcription in the p53-mediated response to DNA damage is modulated by burst frequency.
第一作者:
Dhana,Friedrich
第一单位:
Department for Biology, Technische Universität Darmstadt, Darmstadt, Germany.;Berlin Institute for Medical Systems Biology, Max Delbrück Center in the Helmholtz Association, Berlin, Germany.;Department for Biology, Humboldt Universität zu Berlin, Berlin, Germany.
作者:
主题词
乙酰化作用(Acetylation);细胞核(Cell Nucleus);DNA损伤(DNA Damage);基因表达调控(Gene Expression Regulation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因调控网络(Gene Regulatory Networks);人类(Humans);原位杂交, 荧光(In Situ Hybridization, Fluorescence);赖氨酸(Lysine);模型, 遗传学(Models, Genetic);启动区, 遗传(Promoter Regions, Genetic);辐射, 电离(Radiation, Ionizing);单细胞分析(Single-Cell Analysis);随机过程(Stochastic Processes);转录, 遗传(Transcription, Genetic);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.15252/msb.20199068
PMID
31885199
发布时间
2023-10-20
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