Increased circulatory IL-6 during 8-week fluoxetine treatment is a risk factor for suicidal behaviors in youth.

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作者： Maya,Amitai ^[1] ; Michal,Taler ^[2] ; Reut,Ben-Baruch ^[3] ; Maya,Lebow ^[4] ; Ron,Rotkopf ^[5] ; Alan,Apter ^[6] ; Silvana,Fennig ^[6] ; Abraham,Weizman ^[7] ; Alon,Chen ^[4]

作者单位： The Ruhman Family Laboratory for Research on the Neurobiology of Stress, Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel; Department of Stress Neurobiology and Neurogenetics, Max-Planck Institute of Psychiatry, Munich, Germany; Department of Psychological Medicine, Schneider Children's Medical Center of Israel, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: maya.amitai@weizmann.ac.il. ^[1] Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Petach Tikva, Israel. ^[2] Department of Psychological Medicine, Schneider Children's Medical Center of Israel, Petach Tikva, Israel. ^[3] The Ruhman Family Laboratory for Research on the Neurobiology of Stress, Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel; Department of Stress Neurobiology and Neurogenetics, Max-Planck Institute of Psychiatry, Munich, Germany. ^[4] Bioinformatics Unit, Life Sciences Core Facilities, Weizmann Institute of Science, Israel. ^[5] Department of Psychological Medicine, Schneider Children's Medical Center of Israel, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. ^[6] Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Petach Tikva, Israel; Research Unit, Geha Mental Health Center, Petach Tikva, Israel. ^[7]

关键词 Adolescents Children IL-6 SSRI Suicidality

主题词青少年(Adolescent);儿童(Child);抑郁症, 更年期(Depressive Disorder, Major);女(雌)性(Female);氟西汀(Fluoxetine);人类(Humans);白细胞介素6(Interleukin-6);男(雄)性(Male);危险因素(Risk Factors);自杀意念(Suicidal Ideation)

DOI 10.1016/j.bbi.2019.12.017

PMID 31887416

发布时间 2022-12-07

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Brain, behavior, and immunity

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Increased circulatory IL-6 during 8-week fluoxetine treatment is a risk factor for suicidal behaviors in youth.

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Increased circulatory IL-6 during 8-week fluoxetine treatment is a risk factor for suicidal behaviors in youth.

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