Targeted Inhibition of the Epidermal Growth Factor Receptor and Mammalian Target of Rapamycin Signaling Pathways in Olmsted Syndrome.

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作者： April,Zhang ^[1] ; Sabine,Duchatelet ^[2] ; Nikita,Lakdawala ^[3] ; Richard L,Tower ^[4] ; Carrie,Diamond ^[5] ; Kalyani,Marathe ^[6] ; India,Hill ^[7] ; Gabriele,Richard ^[8] ; Yaser,Diab ^[9] ; Anna Yasmine,Kirkorian ^[6] ; Flora,Watanabe ^[7] ; Dawn H,Siegel ^[10] ; Alain,Hovnanian ^[11]

作者单位： Department of Dermatology, Medical College of Wisconsin, Milwaukee. ^[1] Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1163, Laboratory of Genetic Skin Diseases, Imagine Institute, Paris, France. ^[2] Paris University, Paris, France. ^[3] Ronald O. Perelman Department of Dermatology, New York University, New York. ^[4] Department of Pediatrics (Hematology/Oncology), Medical College of Wisconsin, Milwaukee. ^[5] The George Washington University School of Medicine and Health Sciences, Division of Hematology/Oncology, Children's National Hospital, Washington, DC. ^[6] The George Washington University School of Medicine and Health Sciences, Department of Dermatology, Children's National Hospital, Washington, DC. ^[7] Department of Dermatology, University of Alabama at Birmingham, Birmingham. ^[8] GeneDx, Gaithersburg, Maryland. ^[9] Pediatric Oncology, Hospital Infantil Pequeno Príncipe, Curitiba, Paraná, Brazil. ^[10] Department of Dermatology and Pediatrics (Pediatric Dermatology), Medical College of Wisconsin, Milwaukee. ^[11] Department of Genetics, Necker Hospital, Paris, France. ^[12]

主题词青少年(Adolescent);巴西(Brazil);儿童(Child);儿童, 学龄前(Child, Preschool);女(雌)性(Female);人类(Humans);免疫抑制剂(Immunosuppressive Agents);婴儿(Infant);皮肤角化病, 掌跖(Keratoderma, Palmoplantar);男(雄)性(Male);蛋白激酶抑制剂(Protein Kinase Inhibitors);信号传导(Signal Transduction);西罗莫司(Sirolimus);综合征(Syndrome);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);治疗结果(Treatment Outcome)

DOI 10.1001/jamadermatol.2019.4141

PMID 31895414

发布时间 2021-12-04

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JAMA dermatology

2020年156卷2期

196-200页

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Targeted Inhibition of the Epidermal Growth Factor Receptor and Mammalian Target of Rapamycin Signaling Pathways in Olmsted Syndrome.

JAMA dermatology

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JAMA dermatology

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Targeted Inhibition of the Epidermal Growth Factor Receptor and Mammalian Target of Rapamycin Signaling Pathways in Olmsted Syndrome.

JAMA dermatology

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JAMA dermatology

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