Ubenimex induces autophagy inhibition and EMT suppression to overcome cisplatin resistance in GC cells by perturbing the CD13/EMP3/PI3K/AKT/NF-κB axis.
第一作者:
Qie,Guo
第一单位:
Department of Clinical Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, PR China.
作者:
医学主题词
老年人(Aged);动物(Animals);抗肿瘤药(Antineoplastic Agents);自噬(Autophagy);细胞系, 肿瘤(Cell Line, Tumor);顺铂(Cisplatin);抗药性, 肿瘤(Drug Resistance, Neoplasm);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);人类(Humans);亮氨酸(Leucine);男(雄)性(Male);小鼠, 裸(Mice, Nude);中年人(Middle Aged);信号传导(Signal Transduction);胃肿瘤(Stomach Neoplasms)
DOI
10.18632/aging.102598
PMID
31895687
发布时间
2020-07-06
- 浏览13
Aging
80-105页
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