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首页> Carcinogenesis> A comprehensive in vivo and mathematic modeling-based kinetic characterization for aspirin-induced chemoprevention in colorectal cancer.

A comprehensive in vivo and mathematic modeling-based kinetic characterization for aspirin-induced chemoprevention in colorectal cancer.

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作者： Tadanobu,Shimura ^[1] ; Shusuke,Toden ^[1] ; Natalia L,Komarova ^[2] ; Crichard,Boland ^[1] ; Dominik,Wodarz ^[3] ; Ajay,Goel ^[1]

作者单位： Center for Gastrointestinal Research, Center from Translational Genomics and Oncology, Baylor Scott and White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA. ^[1] Department of Mathematics, University of California, Irvine, CA, USA. ^[2] Department of Population Health and Disease Prevention Program in Public Health Susan and Henry Samueli College of Health Sciences and Department of Mathematics, University of California, Irvine, CA, USA. ^[3] Department of Molecular Diagnostics and Experimental Therapeutics, Beckman Research Institute of City of Hope Comprehensive Cancer Center, Duarte, CA, USA. ^[4]

主题词动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);细胞凋亡(Apoptosis);阿司匹林(Aspirin);细胞增殖(Cell Proliferation);结直肠肿瘤(Colorectal Neoplasms);人类(Humans);动力学(Kinetics);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);模型, 理论(Models, Theoretical);肿瘤细胞, 培养的(Tumor Cells, Cultured);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1093/carcin/bgz195

PMID 31904094

发布时间 2021-07-11

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Carcinogenesis

Carcinogenesis

2020年41卷6期

751-760页

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