Human Tumor-Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing.

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第一作者： Katja,Tuomainen

第一单位： Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.

作者： Katja,Tuomainen ^[1] ; Ahmed,Al-Samadi ^[2] ; Swapnil,Potdar ^[1] ; Laura,Turunen ^[2] ; Minna,Turunen ^[3] ; Piia-Riitta,Karhemo ^[3] ; Paula,Bergman ^[1] ; Maija,Risteli ^[2] ; Pirjo,Åström ^[4] ; Riia,Tiikkaja ^[5] ; Reidar,Grenman ^[6] ; Krister,Wennerberg ^[6] ; Outi,Monni ^[6] ; Tuula,Salo ^[7]

作者单位： Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland. ^[1] Translational Immunology Research Program (TRIMM), University of Helsinki, 00014 Helsinki, Finland. ^[2] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, 00290 Helsinki, Finland. ^[3] Research Programs Unit, Genome-Scale Biology Program and Medicum, Biochemistry and Developmental Biology, University of Helsinki, 00014 Helsinki, Finland. ^[4] Biostatistics Consulting, Department of Public Health, University of Helsinki and Helsinki University Hospital, 00014 Helsinki, Finland. ^[5] Cancer and Translational Medicine Research Unit, University of Oulu, 90014 Oulu, Finland. ^[6] Department of Otorhinolaryngology-Head and Neck Surgery, Turku University Hospital, University of Turku, 20520 Turku, Finland. ^[7] Biotech Research and Innovation Center, Department of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. ^[8] Medical Research Center, Oulu University Hospital, 90014 Oulu, Finland. ^[9] Helsinki University Hospital, 00029 Helsinki, Finland. ^[10]

关键词 clinical trials drug screening head and neck cancer human tumor microenvironment in vitro 3D

DOI 10.3390/cancers12010092

PMID 31905951

发布时间 2020-09-28

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