首页> Annals of oncology : official journal of the European Society for Medical Oncology> Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.

Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.

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第一作者： S,Ugurel

第一单位： Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: selma.ugurel@uk-essen.de.

作者： S,Ugurel ^[1] ; D,Schadendorf ^[2] ; K,Horny ^[3] ; A,Sucker ^[2] ; S,Schramm ^[4] ; J,Utikal ^[5] ; C,Pföhler ^[6] ; R,Herbst ^[7] ; B,Schilling ^[8] ; C,Blank ^[9] ; J C,Becker ^[3] ; A,Paschen ^[2] ; L,Zimmer ^[2] ; E,Livingstone ^[2] ; P A,Horn ^[4] ; V,Rebmann ^[4]

作者单位： Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: selma.ugurel@uk-essen.de. ^[1] Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[2] Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Translational Skin Cancer Research, German Consortium of Translational Cancer Research (DKTK), Essen, Germany. ^[3] Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[4] Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg and Department of Dermatology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany. ^[5] Department of Dermatology, Saarland University Medical Center, Homburg/Saar, Germany. ^[6] Department of Dermatology, Helios Klinikum Erfurt, Erfurt, Germany. ^[7] Department of Dermatology, University Hospital Würzburg, Würzburg, Germany. ^[8] Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands. ^[9]

关键词 PD-1 PD-L1 anti-BRAF therapy anti-PD-1 therapy checkpoint inhibition melanoma

医学主题词人类(Humans);黑色素瘤(Melanoma);肿瘤, 继发原发性(Neoplasms, Second Primary);预后(Prognosis);回顾性研究(Retrospective Studies)

DOI 10.1016/j.annonc.2019.09.005

PMID 31912789

发布时间 2022-05-31

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