Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses.

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作者： Susan M L,Banks ^[1] ; Audrey T,Medeiros ^[1] ; Molly,McQuillan ^[1] ; David J,Busch ^[2] ; Ana Sofia,Ibarraran-Viniegra ^[1] ; Rui,Sousa ^[3] ; Eileen M,Lafer ^[3] ; Jennifer R,Morgan ^[4]

作者单位： The Eugene Bell Center for Regenerative Biology and Tissue Engineering Marine Biological Laboratory, Woods Hole, MA 02543. ^[1] Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712. ^[2] Department of Biochemistry and Structural Biology and Center for Biomedical Neuroscience, the University of Texas Health Science Center at San Antonio, San Antonio, TX 79229. ^[3] The Eugene Bell Center for Regenerative Biology and Tissue Engineering Marine Biological Laboratory, Woods Hole, MA 02543 jmorgan@mbl.edu. ^[4]

关键词 auxilin chaperone clathrin clathrin-coated vesicles endocytosis lamprey

主题词网格蛋白包被小泡(Clathrin-Coated Vesicles);胞吞作用(Endocytosis);人类(Humans);突触(Synapses);突触小泡(Synaptic Vesicles);α突触核蛋白(alpha-Synuclein)

DOI 10.1523/ENEURO.0448-19.2020

PMID 31941659

发布时间 2021-06-18

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