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Enteric infection induces Lark-mediated intron retention at the 5' end of Drosophila genes.

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第一作者： Maroun,Bou Sleiman

第一单位： Laboratory of Integrative Systems Physiology, Institue of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

作者： Maroun,Bou Sleiman ^[1] ; Michael Vincent,Frochaux ^[2] ; Tommaso,Andreani ^[3] ; Dani,Osman ^[4] ; Roderic,Guigo ^[5] ; Bart,Deplancke ^[6]

作者单位： Laboratory of Integrative Systems Physiology, Institue of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. ^[1] Laboratory of System Biology and Genetics and Swiss Institute of Bioinformatics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. ^[2] Computational Biology and Data Mining Group, Institute of Molecular Biology, Ackermannweg 4, 55128, Mainz, Germany. ^[3] Faculty of Sciences III and Azm Center for Research in Biotechnology and its Applications, LBA3B, EDST, Lebanese University, Tripoli, 1300, Lebanon. ^[4] Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003, Barcelona, Catalonia, Spain. ^[5] Laboratory of Integrative Systems Physiology, Institue of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. bart.deplancke@epfl.ch. ^[6]

关键词 DGRP Drosophila melanogaster Gut Infection Intron retention LARK RBM4 Small exon Splicing Systems genetics sQTL