Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes.

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作者： Yuhei,Mizunoe ^[1] ; Masaki,Kobayashi ^[2] ; Shunsuke,Hoshino ^[2] ; Ryoma,Tagawa ^[2] ; Rei,Itagawa ^[2] ; Ayana,Hoshino ^[2] ; Naoyuki,Okita ^[3] ; Yuka,Sudo ^[2] ; Yoshimi,Nakagawa ^[1] ; Hitoshi,Shimano ^[4] ; Yoshikazu,Higami ^[1]

作者单位： Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Ibaraki, Japan. ^[1] Laboratory of Molecular Pathology & Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan. ^[2] Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Yamaguchi Tokyo University of Science, Yamaguchi, Japan. ^[3] International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan. ^[4] Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Ibaraki, Japan. ^[5] AMED-CREST, Japan Agency for Medical Research and Development (AMED), Tokyo, Japan. ^[6] Laboratory of Molecular Pathology & Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan. higami@rs.noda.tus.ac.jp. ^[7]