Liposomal simvastatin sensitizes C26 murine colon carcinoma to the antitumor effects of liposomal 5-fluorouracil in vivo.

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作者： Lavinia,Luput ^[1] ; Alina,Sesarman ^[2] ; Alina,Porfire ^[1] ; Marcela,Achim ^[2] ; Dana,Muntean ^[3] ; Tibor,Casian ^[3] ; Laura,Patras ^[3] ; Valentin Florian,Rauca ^[3] ; Denise Minerva,Drotar ^[1] ; Ioana,Stejerean ^[2] ; Ioan,Tomuta ^[1] ; Laurian,Vlase ^[2] ; Nicolae,Dragos ^[1] ; Vlad Alexandru,Toma ^[1] ; Emilia,Licarete ^[3] ; Manuela,Banciu ^[3]

作者单位： Department of Molecular Biology and Biotechnology, Faculty of Biology and Geology, Babes-Bolyai University, Cluj-Napoca, Romania. ^[1] Molecular Biology Centre, Institute for Interdisciplinary Research in Bio-Nano-Sciences, Babes-Bolyai University, Cluj-Napoca, Romania. ^[2] Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania. ^[3] Taxonomy and Ecology Department, Institute of Biological Research, Cluj-Napoca, Romania. ^[4] National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania. ^[5] Department of Experimental Biology and Biochemistry, Institute of Biological Research Cluj-Napoca, branch of NIRDBS Bucharest, Cluj-Napoca, Romania. ^[6]

关键词 5-fluorouracil combined therapy liposomes resistance simvastatin