首页> Cancers> Resistance to MET/VEGFR2 Inhibition by Cabozantinib Is Mediated by YAP/TBX5-Dependent Induction of FGFR1 in Castration-Resistant Prostate Cancer.

Resistance to MET/VEGFR2 Inhibition by Cabozantinib Is Mediated by YAP/TBX5-Dependent Induction of FGFR1 in Castration-Resistant Prostate Cancer.

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第一作者： Filippos,Koinis

第一单位： Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

作者： Filippos,Koinis ^[1] ; Paul,Corn ^[1] ; Nila,Parikh ^[1] ; Jian,Song ^[1] ; Ioulia,Vardaki ^[1] ; Ioanna,Mourkioti ^[1] ; Sue-Hwa,Lin ^[2] ; Christopher,Logothetis ^[1] ; Theocharis,Panaretakis ^[1] ; Gary,Gallick ^[1]

作者单位： Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[1] Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.;Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[2]

关键词 FGFR1 TBX5 YAP c-MET cabozantinib prostate cancer resistance

DOI 10.3390/cancers12010244

PMID 31963871

发布时间 2020-09-28

基金项目

RP 150282/Cancer Prevention Research Institute of Texas P50 CA140388/CA/NCI NIH HHS/United States R01 CA174798/CA/NCI NIH HHS/United States NIH 5P50CA140388/GF/NIH HHS/United States NIH R01CA174798/GF/NIH HHS/United States RP150179/Cancer Prevention Research Institute of Texas

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