<i>Urocortin 2</i> Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency.

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作者： Mei Hua,Gao ^[1] ; Dimosthenis,Giamouridis ^[2] ; N Chin,Lai ^[1] ; Tracy,Guo ^[2] ; Bing,Xia ^[3] ; Young Chul,Kim ^[1] ; Viet Anh Nguyen,Huu ^[2] ; Dorota,Skowronska-Krawczyk ^[1] ; Louise,Lantier ^[2] ; Raag,Bhargava ^[1] ; H Kirk,Hammond ^[2]

作者单位： Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA. ^[1] Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA. ^[2] Department of Pharmacology and Toxicology, Cardiovascular Research Institute, Maastricht University, 6200 MD Maastricht, the Netherlands. ^[3] Department of Ophthalmology, University of California, San Diego, San Diego, CA 92103, USA. ^[4] Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, TN 37232-0615, USA. ^[5]

关键词 AMP-activated protein kinase Akita Mouse Akt Diabetic retinopathy Gene therapy Insulin sensitivity Intravenous AAV8 Islet insulin release Type 1 diabetes

DOI 10.1016/j.omtm.2019.12.002

PMID 31970200

发布时间 2024-04-22

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Molecular therapy. Methods & clinical development

2020年17卷

220-233页

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<i>Urocortin 2</i> Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

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<i>Urocortin 2</i> Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

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