Targeting PPAR ligands as possible approaches for metabolic reprogramming of T cells in cancer immunotherapy.

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第一作者： Saman,Bahrambeigi

第一单位： Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran.

作者： Saman,Bahrambeigi ^[1] ; Morteza,Molaparast ^[1] ; Farahnaz,Sohrabi ^[2] ; Lachin,Seifi ^[3] ; Alireza,Faraji ^[3] ; Saba,Fani ^[3] ; Vahid,Shafiei-Irannejad ^[4]

作者单位： Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran. ^[1] Department of Clinical Biochemistry, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran. ^[2] Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran. ^[3] Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran. Electronic address: Shafiei.v@umsu.ac.ir. ^[4]

关键词 Metabolic reprogramming PPAR ligands T cell metabolism Tumor microenvironment

主题词人类(Humans);免疫疗法(Immunotherapy);配体(Ligands);肿瘤(Neoplasms);过氧化物酶体增殖物激活受体(Peroxisome Proliferator-Activated Receptors);T淋巴细胞(T-Lymphocytes);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/j.imlet.2020.01.006

PMID 31982460

发布时间 2020-12-17

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