首页> International journal of pharmaceutics> Facile nose-to-brain delivery of rotigotine-loaded polymer micelles thermosensitive hydrogels: In vitro characterization and in vivo behavior study.

Facile nose-to-brain delivery of rotigotine-loaded polymer micelles thermosensitive hydrogels: In vitro characterization and in vivo behavior study.

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第一作者： Fangyuan,Wang

第一单位： Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.

作者： Fangyuan,Wang ^[1] ; Zhuanzhuan,Yang ^[1] ; Mengli,Liu ^[1] ; Yaotian,Tao ^[2] ; Zhenbao,Li ^[2] ; Zonghao,Wu ^[3] ; Shuangying,Gui ^[4]

作者单位： Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China. ^[1] Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China; Institute of Pharmaceutics, Anhui Academy of Chinese Medicine, Hefei, China; Engineering Technology Research Center of Modernized Pharmaceutics, AnHui Province, China. ^[2] Hefei Huafang Pharmaceutical Science & Technology Co., Ltd., Hefei 230088, China. ^[3] Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China; Institute of Pharmaceutics, Anhui Academy of Chinese Medicine, Hefei, China; Engineering Technology Research Center of Modernized Pharmaceutics, AnHui Province, China. Electronic address: guishy0520@126.com. ^[4]

关键词 Brain targeting Nasal delivery system Polymeric micelles Rotigotine Thermosensitive gels