Ultrasound-mediated delivery of miRNA-122 and anti-miRNA-21 therapeutically immunomodulates murine hepatocellular carcinoma in vivo.

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第一作者： Jennifer C,Wischhusen

第一单位： Apoptosis, Cancer and Development Laboratory, Centre de Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Centre Léon Bérard, 69008 Lyon, France; Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA.

作者： Jennifer C,Wischhusen ^[1] ; Sayan Mullick,Chowdhury ^[2] ; Taehwa,Lee ^[2] ; Huaijun,Wang ^[3] ; Sunitha,Bachawal ^[4] ; Rammohan,Devulapally ^[2] ; Rayhaneh,Afjei ^[5] ; Uday Kumar,Sukumar ^[6] ; Ramasamy,Paulmurugan ^[7]

作者单位： Apoptosis, Cancer and Development Laboratory, Centre de Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Centre Léon Bérard, 69008 Lyon, France; Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA. ^[1] Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA. ^[2] Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA. Electronic address: whjwang@stanford.edu. ^[3] Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA. Electronic address: bachawal@stanford.edu. ^[4] Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA. Electronic address: rafjei@stanford.edu. ^[5] Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA. Electronic address: udkr8817@stanford.edu. ^[6] Department of Radiology, School of Medicine, Stanford University, Stanford, CA, USA. Electronic address: paulmur8@stanford.edu. ^[7]

关键词 Cytokine screening Local drug delivery Poly (lactic-co-glycolic acid) nanoparticles Tumor immune response Ultrasound-targeted microbubble destruction