Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.

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第一作者： Simone,Ragusa

第一单位： Department of Oncology, University of Lausanne and CHUV, Epalinges, Switzerland.

作者： Simone,Ragusa ^[1] ; Borja,Prat-Luri ^[2] ; Alejandra,González-Loyola ^[1] ; Sina,Nassiri ^[2] ; Mario Leonardo,Squadrito ^[1] ; Alan,Guichard ^[2] ; Sabrina,Cavin ^[3] ; Nikolce,Gjorevski ^[4] ; David,Barras ^[4] ; Giancarlo,Marra ^[4] ; Matthias P,Lutolf ^[5] ; Jean,Perentes ^[6] ; Emily,Corse ^[3] ; Roberta,Bianchi ^[7] ; Laureline,Wetterwald ^[6] ; Jaeryung,Kim ^[5] ; Guillermo,Oliver ^[8] ; Mauro,Delorenzi ^[8] ; Michele,De Palma ^[1] ; Tatiana V,Petrova ^[2]

作者单位： Department of Oncology, University of Lausanne and CHUV, Epalinges, Switzerland. ^[1] Ludwig Institute for Cancer Research Lausanne, Epalinges, Switzerland. ^[2] Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland. ^[3] Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland. ^[4] Division of Thoracic Surgery, CHUV, Lausanne, Switzerland. ^[5] Institute of Bioengineering, School of Life Sciences, EPFL, Lausanne, Switzerland. ^[6] Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland. ^[7] Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, (pRED), Schlieren, Switzerland. ^[8] Center for Vascular and Developmental Biology, Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. ^[9]

关键词 Angiogenesis Cancer immunotherapy Colorectal cancer Oncology endothelial cells